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The Chlamydia effector CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35

The obligate intracellular bacterium Chlamydia trachomatis inserts a family of inclusion membrane (Inc) proteins into the membrane of its vacuole (the inclusion). The Inc CpoS is a critical suppressor of host cellular immune surveillance, but the underlying mechanism remained elusive. By complementi...

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Detalles Bibliográficos
Autores principales: Meier, Karsten, Jachmann, Lana H., Türköz, Gözde, Babu Sait, Mohammed Rizwan, Pérez, Lucía, Kepp, Oliver, Valdivia, Raphael H., Kroemer, Guido, Sixt, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470785/
https://www.ncbi.nlm.nih.gov/pubmed/37530528
http://dx.doi.org/10.1128/mbio.03190-22