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Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia

INTRODUCTION: The suitability of whole-genome sequencing (WGS) as the sole method to detect clinically relevant genomic aberrations in B-cell acute lymphoblastic leukemia (ALL) was investigated with the aim of replacing current diagnostic methods. METHODS: For this purpose, we assessed the analytica...

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Detalles Bibliográficos
Autores principales: Rezayee, Fatemah, Eisfeldt, Jesper, Skaftason, Aron, Öfverholm, Ingegerd, Sayyab, Shumaila, Syvänen, Ann Christine, Maqbool, Khurram, Lilljebjörn, Henrik, Johansson, Bertil, Olsson-Arvidsson, Linda, Pietras, Christina Orsmark, Staffas, Anna, Palmqvist, Lars, Fioretos, Thoas, Cavelier, Lucia, Fogelstrand, Linda, Nordlund, Jessica, Wirta, Valtteri, Rosenquist, Richard, Barbany, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470829/
https://www.ncbi.nlm.nih.gov/pubmed/37664045
http://dx.doi.org/10.3389/fonc.2023.1217712