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α4-Containing GABA(A) Receptors on DRD2 Neurons of the Nucleus Accumbens Mediate Instrumental Responding for Conditioned Reinforcers and Its Potentiation by Cocaine

Extrasynaptic GABA(A) receptors (GABA(A)Rs) composed of α4, β, and δ subunits mediate GABAergic tonic inhibition and are potential molecular targets in the modulation of behavioral responses to natural and drug rewards. These GABA(A)Rs are highly expressed within the nucleus accumbens (NAc), where t...

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Detalles Bibliográficos
Autores principales: Macpherson, Tom, Dixon, Claire I., Robertson, Jonathan, Sindarto, Marsha M., Janak, Patricia H., Belelli, Delia, Lambert, Jeremy J., Stephens, David N., King, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470850/
https://www.ncbi.nlm.nih.gov/pubmed/37553242
http://dx.doi.org/10.1523/ENEURO.0236-23.2023