NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis

Cutaneous leishmaniasis exhibits a spectrum of clinical presentations dependent upon the parasites’ persistence and host immunopathologic responses. Although cytolytic CD8 T cells cannot control the parasites, they significantly contribute to pathologic responses. In a murine model of cutaneous leis...

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Detalles Bibliográficos
Autores principales: Sacramento, Laís A., Farias Amorim, Camila, Campos, Taís M., Saldanha, Maíra, Arruda, Sérgio, Carvalho, Lucas P., Beiting, Daniel P., Carvalho, Edgar M., Novais, Fernanda O., Scott, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470908/
https://www.ncbi.nlm.nih.gov/pubmed/37603573
http://dx.doi.org/10.1371/journal.pntd.0011552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470908/
https://www.ncbi.nlm.nih.gov/pubmed/37603573
http://dx.doi.org/10.1371/journal.pntd.0011552

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