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A subcomponent-guided deep learning method for interpretable cancer drug response prediction

Accurate prediction of cancer drug response (CDR) is a longstanding challenge in modern oncology that underpins personalized treatment. Current computational methods implement CDR prediction by modeling responses between entire drugs and cell lines, without the consideration that response outcomes m...

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Detalles Bibliográficos
Autores principales: Liu, Xuan, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470940/
https://www.ncbi.nlm.nih.gov/pubmed/37603576
http://dx.doi.org/10.1371/journal.pcbi.1011382