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Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination

Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we repor...

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Detalles Bibliográficos
Autores principales: Lemieux, Jacob E., Huang, Weihua, Hill, Nathan, Cerar, Tjasa, Freimark, Lisa, Hernandez, Sergio, Luban, Matteo, Maraspin, Vera, Bogovič, Petra, Ogrinc, Katarina, Ruzič-Sabljič, Eva, Lapierre, Pascal, Lasek-Nesselquist, Erica, Singh, Navjot, Iyer, Radha, Liveris, Dionysios, Reed, Kurt D., Leong, John M., Branda, John A., Steere, Allen C., Wormser, Gary P., Strle, Franc, Sabeti, Pardis C., Schwartz, Ira, Strle, Klemen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470944/
https://www.ncbi.nlm.nih.gov/pubmed/37651316
http://dx.doi.org/10.1371/journal.ppat.1011243