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Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis

BACKGROUND: Autoimmune diseases often have strong genetic associations with specific HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked upregulation of HLA-DR molecules, including in postinfectious Lyme arthritis (LA). However, the identity of HLA-DR–presente...

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Detalles Bibliográficos
Autores principales: Kanjana, Korawit, Strle, Klemen, Lochhead, Robert B., Pianta, Annalisa, Mateyka, Laura M., Wang, Qi, Arvikar, Sheila L., Kling, David E., Deangelo, Cameron A., Curham, Lucy, Barbour, Alan G., Costello, Catherine E., Moon, James J., Steere, Allen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471169/
https://www.ncbi.nlm.nih.gov/pubmed/37471146
http://dx.doi.org/10.1172/JCI161170