SAP30 promotes breast tumor progression by bridging the transcriptional corepressor SIN3 complex and MLL1

SAP30 is a core subunit of the transcriptional corepressor SIN3 complex, but little is known about its role in gene regulation and human cancer. Here, we show that SAP30 was a nonmutational oncoprotein upregulated in more than 50% of human breast tumors and correlated with unfavorable outcomes in pa...

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Detalles Bibliográficos
Autores principales: Bao, Lei, Kumar, Ashwani, Zhu, Ming, Peng, Yan, Xing, Chao, Wang, Jennifer E., Wang, Yingfei, Luo, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471174/
https://www.ncbi.nlm.nih.gov/pubmed/37655663
http://dx.doi.org/10.1172/JCI168362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471174/
https://www.ncbi.nlm.nih.gov/pubmed/37655663
http://dx.doi.org/10.1172/JCI168362

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