Species-specific protein–protein interactions govern the humanization of the 20S proteasome in yeast

Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunits are “humanizable,” except subunits compri...

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Detalles Bibliográficos
Autores principales: Sultana, Sarmin, Abdullah, Mudabir, Li, Jianhui, Hochstrasser, Mark, Kachroo, Aashiq H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471208/
https://www.ncbi.nlm.nih.gov/pubmed/37364278
http://dx.doi.org/10.1093/genetics/iyad117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471208/
https://www.ncbi.nlm.nih.gov/pubmed/37364278
http://dx.doi.org/10.1093/genetics/iyad117

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