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Species-specific protein–protein interactions govern the humanization of the 20S proteasome in yeast
Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunits are “humanizable,” except subunits compri...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471208/ https://www.ncbi.nlm.nih.gov/pubmed/37364278 http://dx.doi.org/10.1093/genetics/iyad117 |