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Thiostrepton-Nanomedicine, a TLR9 Inhibitor, Attenuates Sepsis-Induced Inflammation in Mice

Sepsis is a life-threatening clinical condition caused by infection and transposition of pathogens and pathogen-associated molecular patterns (PAMPs) into the host bloodstream. During sepsis, activation of toll-like receptors (TLRs) on immune cells triggers the release of pro-inflammatory cytokines...

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Detalles Bibliográficos
Autores principales: Esparza, K., Oliveira, S. D., Castellon, M., Minshall, R. D., Onyuksel, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471450/
https://www.ncbi.nlm.nih.gov/pubmed/37662481
http://dx.doi.org/10.1155/2023/4035516