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Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NFκB Signal in Mice

Acetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in several animal disease models. In the present study,...

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Detalles Bibliográficos
Autores principales: Du, Hui, Tong, Shiwen, Kuang, Ge, Gong, Xia, Jiang, Ningman, Yang, Xian, Liu, Hao, Li, Nana, Xie, Yao, Xiang, Yang, Guo, Jiashi, Li, Zhenhan, Yuan, Yinglin, Wu, Shengwang, Wan, Jingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471453/
https://www.ncbi.nlm.nih.gov/pubmed/37663051
http://dx.doi.org/10.1155/2023/1116841