Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis

The molecular etiology of idiopathic pulmonary fibrosis (IPF) has been extensively investigated to identify new therapeutic targets. Although anti-inflammatory treatments are not effective for patients with IPF, damaged alveolar epithelial cells play a critical role in lung fibrogenesis. Here, we es...

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Detalles Bibliográficos
Autores principales: Enomoto, Yasunori, Katsura, Hiroaki, Fujimura, Takashi, Ogata, Akira, Baba, Saori, Yamaoka, Akira, Kihara, Miho, Abe, Takaya, Nishimura, Osamu, Kadota, Mitsutaka, Hazama, Daisuke, Tanaka, Yugo, Maniwa, Yoshimasa, Nagano, Tatsuya, Morimoto, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471635/
https://www.ncbi.nlm.nih.gov/pubmed/37653024
http://dx.doi.org/10.1038/s41467-023-40617-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471635/
https://www.ncbi.nlm.nih.gov/pubmed/37653024
http://dx.doi.org/10.1038/s41467-023-40617-y

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