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TAK1 Reduces Surgery-induced Overactivation of RIPK1 to Relieve Neuroinflammation and Cognitive Dysfunction in Aged Rats

Background: Postoperative cognitive dysfunction (POCD) is a common clinical complication in elderly patients, but its underlying mechanism remains unclear. Receptor-interacting protein kinase 1 (RIPK1), a key molecule mediating necroptosis and regulated by transforming growth factor β-activated kina...

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Detalles Bibliográficos
Autores principales: Zhang, Yuhan, Su, Yang, Wang, Ziheng, Li, Teng, Wang, Liwei, Ma, Daqing, Zhou, Meiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471686/
https://www.ncbi.nlm.nih.gov/pubmed/37329446
http://dx.doi.org/10.1007/s11064-023-03959-z