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Purinergic neurotransmission receptor P2X4 silencing alleviates intracerebral hemorrhage-induced neuroinflammation by blocking the NLRP1/Caspase-1 pathway

This study is performed to explore the role of P2X4 in intracerebral hemorrhage (ICH) and the association between P2X4 and the NLRP1/Caspase-1 pathway. The mouse ICH model was established via collagenase injection into the right basal ganglia. P2X4 expression in brain tissues was knocked down via in...

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Detalles Bibliográficos
Autores principales: Wu, Yuanshui, Huang, Xiaoli, Yang, Le, Liu, Yuanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471699/
https://www.ncbi.nlm.nih.gov/pubmed/37652931
http://dx.doi.org/10.1038/s41598-023-40748-8