Targeted inhibition of eIF5A(hpu) suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer

Eukaryotic initiation factor 5A2 (eIF5A2) is overexpressed in many types of cancer, and spermidine-mediated eIF5A hypusination (eIF5A(hpu)) appears to be essential to most of eIF5A’s biological functions, including its important role in regulating cancer cell proliferation, epithelial–mesenchymal tr...

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Detalles Bibliográficos
Autores principales: Zeng, Jincheng, Ye, Ziyu, Shi, Shihong, Liang, Yanfang, Meng, Qingyu, Zhang, Qunzhou, Le, Anh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471704/
https://www.ncbi.nlm.nih.gov/pubmed/37653021
http://dx.doi.org/10.1038/s41419-023-06109-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471704/
https://www.ncbi.nlm.nih.gov/pubmed/37653021
http://dx.doi.org/10.1038/s41419-023-06109-z

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