Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy

This article describes the critical role of neurosteroids in postpartum depression (PPD) and outlines the landmark pharmacological journey of brexanolone as a first-in-class neurosteroid antidepressant with significant advantages over traditional antidepressants. PPD is a neuroendocrine disorder tha...

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Detalles Bibliográficos
Autores principales: Reddy, Doodipala Samba, Mbilinyi, Robert H., Estes, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471722/
https://www.ncbi.nlm.nih.gov/pubmed/37566239
http://dx.doi.org/10.1007/s00213-023-06427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471722/
https://www.ncbi.nlm.nih.gov/pubmed/37566239
http://dx.doi.org/10.1007/s00213-023-06427-2

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