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Evolution of termination codons of proteins and the TAG-TGA paradox

In most eukaryotes and prokaryotes TGA is used at a significantly higher frequency than TAG as termination codon of protein-coding genes. Although this phenomenon has been recognized several years ago, there is no generally accepted explanation for the TAG-TGA paradox. Our analyses of human mutation...

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Detalles Bibliográficos
Autores principales: Trexler, Mária, Bányai, László, Kerekes, Krisztina, Patthy, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471768/
https://www.ncbi.nlm.nih.gov/pubmed/37653005
http://dx.doi.org/10.1038/s41598-023-41410-z