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Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis

Systemic sclerosis (SSc) is an autoimmune, inflammatory and fibrotic disease with limited treatment options. Developing new therapies is therefore crucial to address patient needs. To this end, we focused on galectin-3 (Gal-3), a lectin known to be associated with several pathological processes seen...

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Detalles Bibliográficos
Autores principales: Ortega-Ferreira, Céline, Soret, Perrine, Robin, Gautier, Speca, Silvia, Hubert, Sandra, Le Gall, Marianne, Desvaux, Emiko, Jendoubi, Manel, Saint-Paul, Julie, Chadli, Loubna, Chomel, Agnès, Berger, Sylvie, Nony, Emmanuel, Neau, Béatrice, Fould, Benjamin, Licznar, Anne, Levasseur, Franck, Guerrier, Thomas, Elouej, Sahar, Courtade-Gaïani, Sophie, Provost, Nicolas, Nguyen, The Quyen, Verdier, Julien, Launay, David, De Ceuninck, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471779/
https://www.ncbi.nlm.nih.gov/pubmed/37652913
http://dx.doi.org/10.1038/s41467-023-41117-9