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Ancestral diversity in lipoprotein(a) studies helps address evidence gaps

INTRODUCTION: The independent and causal cardiovascular disease risk factor lipoprotein(a) (Lp(a)) is elevated in >1.5 billion individuals worldwide, but studies have prioritised European populations. METHODS: Here, we examined how ancestrally diverse studies could clarify Lp(a)’s genetic archite...

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Detalles Bibliográficos
Autores principales: Lee, Moa P, Dimos, Sofia F, Raffield, Laura M, Wang, Zhe, Ballou, Anna F, Downie, Carolina G, Arehart, Christopher H, Correa, Adolfo, de Vries, Paul S, Du, Zhaohui, Gignoux, Christopher R, Gordon-Larsen, Penny, Guo, Xiuqing, Haessler, Jeffrey, Howard, Annie Green, Hu, Yao, Kassahun, Helina, Kent, Shia T, Lopez, J Antonio G, Monda, Keri L, North, Kari E, Peters, Ulrike, Preuss, Michael H, Rich, Stephen S, Rhodes, Shannon L, Yao, Jie, Yarosh, Rina, Tsai, Michael Y, Rotter, Jerome I, Kooperberg, Charles L, Loos, Ruth J F, Ballantyne, Christie, Avery, Christy L, Graff, Mariaelisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471864/
https://www.ncbi.nlm.nih.gov/pubmed/37648373
http://dx.doi.org/10.1136/openhrt-2023-002382