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Coherent pathway enrichment estimation by modeling inter-pathway dependencies using regularized regression

MOTIVATION: Gene set enrichment methods are a common tool to improve the interpretability of gene lists as obtained, for example, from differential gene expression analyses. They are based on computing whether dysregulated genes are located in certain biological pathways more often than expected by...

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Detalles Bibliográficos
Autores principales: Jablonski, Kim Philipp, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471899/
https://www.ncbi.nlm.nih.gov/pubmed/37610338
http://dx.doi.org/10.1093/bioinformatics/btad522