A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura

Immune-mediated thrombotic thrombocytopenic purpura (iTTP), an autoantibody-mediated severe ADAMTS13 deficiency, is caused by insufficient proteolytic processing of von Willebrand factor (VWF) multimers (MMs) and microvascular thrombi. Recurrence of acute iTTP is associated with persistence or reapp...

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Detalles Bibliográficos
Autores principales: Falter, Tanja, Rossmann, Heidi, de Waele, Laure, Dekimpe, Charlotte, von Auer, Charis, Müller-Calleja, Nadine, Häuser, Friederike, Degreif, Adriana, Marandiuc, Dana, Messmer, Xavier, Sprinzl, Martin, Lackner, Karl J., Jurk, Kerstin, Vanhoorelbeke, Karen, Lämmle, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471935/
https://www.ncbi.nlm.nih.gov/pubmed/37399489
http://dx.doi.org/10.1182/bloodadvances.2023010028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471935/
https://www.ncbi.nlm.nih.gov/pubmed/37399489
http://dx.doi.org/10.1182/bloodadvances.2023010028

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