Subclonal TP53 mutations are frequent and predict resistance to radioimmunotherapy in follicular lymphoma

Although TP53 is commonly mutated in transformed follicular lymphoma, mutations are reported in <5% of pretreatment follicular lymphoma (FL) specimens. We assayed archival follicular B-cell non-Hodgkin lymphoma specimens from a completed clinical trial, Southwest Oncology Group S0016, a phase 3 r...

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Detalles Bibliográficos
Autores principales: Burack, W. Richard, Li, Hongli, Adlowitz, Diana, Spence, Janice M., Rimsza, Lisa M., Shadman, Mazyar, Spier, Catherine M., Kaminski, Mark S., Leonard, John P., Leblanc, Michael L., Smith, Sonali M., Friedberg, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471938/
https://www.ncbi.nlm.nih.gov/pubmed/37379264
http://dx.doi.org/10.1182/bloodadvances.2022009467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471938/
https://www.ncbi.nlm.nih.gov/pubmed/37379264
http://dx.doi.org/10.1182/bloodadvances.2022009467

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