Allele-specific quantification of human leukocyte antigen transcript isoforms by nanopore sequencing

INTRODUCTION: While tens of thousands of HLA alleles have been identified by DNA sequencing, the contribution of alternative splicing to HLA diversity is not well characterized. In this study, we sought to determine if long-read sequencing could be used to accurately quantify allele-specific HLA tra...

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Detalles Bibliográficos
Autores principales: Hughes, Andrew E. O., Montgomery, Maureen C., Liu, Chang, Weimer, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471969/
https://www.ncbi.nlm.nih.gov/pubmed/37662944
http://dx.doi.org/10.3389/fimmu.2023.1199618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471969/
https://www.ncbi.nlm.nih.gov/pubmed/37662944
http://dx.doi.org/10.3389/fimmu.2023.1199618

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