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ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma

INTRODUCTION: Metastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic strategies. Applying chimeric antigen receptor (CAR) technology to natural killer (NK) cells may of...

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Detalles Bibliográficos
Autores principales: Heim, Catrin, Moser, Laura M., Kreyenberg, Herman, Bonig, Halvard B., Tonn, Torsten, Wels, Winfried S., Gradhand, Elise, Ullrich, Evelyn, Meister, Michael T., Koerkamp, Marian Groot, Holstege, Frank C. P., Drost, Jarno, Klusmann, Jan-Henning, Bader, Peter, Merker, Michael, Rettinger, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471977/
https://www.ncbi.nlm.nih.gov/pubmed/37662907
http://dx.doi.org/10.3389/fimmu.2023.1228894