Clec4A4 Acts as a Negative Immune Checkpoint Regulator to Suppress Antitumor Immunity

Clec4A4 is a C-type lectin receptor (CLR) exclusively expressed on murine conventional dendritic cells (cDC) to regulate their activation status. However, the functional role of murine Clec4A4 (mClec4A4) in antitumor immunity remains unclear. Here, we show that mClec4A4 serves as a negative immune c...

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Detalles Bibliográficos
Autores principales: Uto, Tomofumi, Fukaya, Tomohiro, Mitoma, Shuya, Nishikawa, Yotaro, Tominaga, Moe, Choijookhuu, Narantsog, Hishikawa, Yoshitaka, Sato, Katsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472101/
https://www.ncbi.nlm.nih.gov/pubmed/37432112
http://dx.doi.org/10.1158/2326-6066.CIR-22-0536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472101/
https://www.ncbi.nlm.nih.gov/pubmed/37432112
http://dx.doi.org/10.1158/2326-6066.CIR-22-0536

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