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Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis

Triple-negative breast cancers (TNBC) tend to become invasive and metastatic at early stages in their development. Despite some treatment successes in early-stage localized TNBC, the rate of distant recurrence remains high, and long-term survival outcomes remain poor. In a search for new therapeutic...

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Detalles Bibliográficos
Autores principales: Mukherjee, Debarati, Previs, Rebecca A., Haines, Corinne, Al Abo, Muthana, Juras, Patrick K., Strickland, Kyle C., Chakraborty, Binita, Artham, Sandeep, Whitaker, Regina S., Hebert, Katherine, Fontenot, Jake, Patierno, Steven R., Freedman, Jennifer A., Lau, Frank H., Burow, Matthew E., Chang, Ching-Yi, McDonnell, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472110/
https://www.ncbi.nlm.nih.gov/pubmed/37335130
http://dx.doi.org/10.1158/0008-5472.CAN-22-1622