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Recombinant VEGF-C (Cys156Ser) improves mesenteric lymphatic drainage and gut immune surveillance in experimental cirrhosis

BACKGROUND & AIMS: Lymphatic vessels (LVs) are crucial for maintaining abdominal fluid homoeostasis and immunity. In cirrhosis, mesenteric LVs (mLVs) are dilated and dysfunctional. Given the established role of vascular endothelial growth factor-C (VEGF-C) in improving LVs, we hypothesised that...

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Detalles Bibliográficos
Autores principales: Juneja, Pinky, Ruhina Rahman, Syed Nazrin, Jakhar, Deepika, Mourya, Akash Kumar, Tripathi, Dinesh M., Kaur, Impreet, Tiwari, Vaibhav, Rohilla, Sumati, Gupta, Abhishek, Rawal, Preety, Baweja, Sukriti, Rastogi, Archana, Naidu, V.G.M., Sarin, Shiv K., Banerjee, Subham, Kaur, Savneet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472308/
https://www.ncbi.nlm.nih.gov/pubmed/37663117
http://dx.doi.org/10.1016/j.jhepr.2023.100816