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IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

INTRODUCTION: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains largely unknown. MATERIALS AND METHODS: The Gen...

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Detalles Bibliográficos
Autores principales: Qin, Jian, Cui, Zheng, Zhou, Jingyi, Zhang, Bosen, Lu, Ruiqi, Ding, Youcheng, Hu, Hai, Cai, Jingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472310/
https://www.ncbi.nlm.nih.gov/pubmed/37643553
http://dx.doi.org/10.1016/j.tranon.2023.101764