Cargando…

Nanoscale Metal–Organic Framework with an X-ray Triggerable Prodrug for Synergistic Radiotherapy and Chemotherapy

[Image: see text] As heavy-metal-based nanoscale metal–organic frameworks (nMOFs) are excellent radiosensitizers for radiotherapy via enhanced energy deposition and reactive oxygen species (ROS) generation, we hypothesize that nMOFs with covalently conjugated and X-ray triggerable prodrugs can harne...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ziwan, Zhen, Wenyao, McCleary, Caroline, Luo, Taokun, Jiang, Xiaomin, Peng, Cheng, Weichselbaum, Ralph R., Lin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472429/
https://www.ncbi.nlm.nih.gov/pubmed/37581644
http://dx.doi.org/10.1021/jacs.3c04602