A Conserved Second Sphere Residue Tunes Copper Site Reactivity in Lytic Polysaccharide Monooxygenases

[Image: see text] Lytic polysaccharide monooxygenases (LPMOs) are powerful monocopper enzymes that can activate strong C–H bonds through a mechanism that remains largely unknown. Herein, we investigated the role of a conserved glutamine/glutamate in the second coordination sphere. Mutation of the Gl...

Descripción completa

Detalles Bibliográficos
Autores principales: Hall, Kelsi R., Joseph, Chris, Ayuso-Fernández, Iván, Tamhankar, Ashish, Rieder, Lukas, Skaali, Rannei, Golten, Ole, Neese, Frank, Røhr, Åsmund K., Jannuzzi, Sergio A. V., DeBeer, Serena, Eijsink, Vincent G. H., Sørlie, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472438/
https://www.ncbi.nlm.nih.gov/pubmed/37584157
http://dx.doi.org/10.1021/jacs.3c05342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472438/
https://www.ncbi.nlm.nih.gov/pubmed/37584157
http://dx.doi.org/10.1021/jacs.3c05342

Ejemplares similares