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DNA methylation patterns in CD4(+) T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis

BACKGROUND: Psoriasis is an autoimmune/inflammatory disorder primarily affecting the skin. Chronic joint inflammation triggers the diagnosis of psoriatic arthritis (PsA) in approximately one-third of psoriasis patients. Although joint disease typically follows the onset of skin psoriasis, in around...

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Detalles Bibliográficos
Autores principales: Natoli, Valentina, Charras, Amandine, Hofmann, Sigrun R., Northey, Sarah, Russ, Susanne, Schulze, Felix, McCann, Liza, Abraham, Susanne, Hedrich, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472451/
https://www.ncbi.nlm.nih.gov/pubmed/37662940
http://dx.doi.org/10.3389/fimmu.2023.1245876