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Bioavailable Sulforaphane Quantitation in Plasma by LC–MS/MS Is Enhanced by Blocking Thiols

[Image: see text] Quantifying sulforaphane (SFN) and its thiol metabolites in biological samples using liquid chromatography–tandem mass spectrometry is complicated by SFN’s electrophilic nature and the facile dissociation of SFN-thiol conjugates. SFN can be lost during sample preparation due to con...

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Detalles Bibliográficos
Autores principales: Grady, Rachel S., Traustadóttir, Tinna, Lagalante, Anthony F., Eggler, Aimee L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472501/
https://www.ncbi.nlm.nih.gov/pubmed/37584212
http://dx.doi.org/10.1021/acs.jafc.3c01367