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Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries

[Image: see text] Discovering new bioactive molecules is crucial for drug development. Finding a hit compound for a new drug target usually requires screening of millions of molecules. Affinity selection based technologies have revolutionized early hit discovery by enabling the rapid screening of li...

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Detalles Bibliográficos
Autores principales: Mata, J. Miguel, van der Nol, Edith, Pomplun, Sebastian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472510/
https://www.ncbi.nlm.nih.gov/pubmed/37556835
http://dx.doi.org/10.1021/jacs.3c04899