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Single‐cell transcriptomics implicates the FEZ1–DKK1 axis in the regulation of corneal epithelial cell proliferation and senescence

Limbal stem/progenitor cells (LSC) represent the source of corneal epithelium renewal. LSC proliferation and differentiation are essential for corneal homeostasis, however, the regulatory mechanism remains largely unexplored. Here, we performed single‐cell RNA sequencing and discovered proliferation...

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Detalles Bibliográficos
Autores principales: Zhu, Liqiong, Wang, Li, Liu, Dongmei, Chen, Chaoqun, Mo, Kunlun, Lan, Xihong, Liu, Jiafeng, Huang, Ying, Guo, Dianlei, Huang, Huaxing, Li, Mingsen, Guo, Huizhen, Tan, Jieying, Zhang, Kang, Ji, Jianping, Yuan, Jin, Ouyang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472519/
https://www.ncbi.nlm.nih.gov/pubmed/36851859
http://dx.doi.org/10.1111/cpr.13433