Simple and validated method to quantify lacosamide in human breast milk and plasma using UPLC/MS/MS and its application to estimate drug transfer into breast milk

BACKGROUND: Epilepsy is a common neurological disorder. Lacosamide is a third-generation antiepileptic drug used to treat partial-onset seizures. Limited information is currently available on the transfer of lacosamide to breast milk. To facilitate studies on the safety of lacosamide use during brea...

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Detalles Bibliográficos
Autores principales: Furugen, Ayako, Nishimura, Ayako, Umazume, Takeshi, Ishikawa, Hina, Narumi, Katsuya, Kobayashi, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472561/
https://www.ncbi.nlm.nih.gov/pubmed/37653499
http://dx.doi.org/10.1186/s40780-023-00295-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472561/
https://www.ncbi.nlm.nih.gov/pubmed/37653499
http://dx.doi.org/10.1186/s40780-023-00295-w

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