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Simple and validated method to quantify lacosamide in human breast milk and plasma using UPLC/MS/MS and its application to estimate drug transfer into breast milk
BACKGROUND: Epilepsy is a common neurological disorder. Lacosamide is a third-generation antiepileptic drug used to treat partial-onset seizures. Limited information is currently available on the transfer of lacosamide to breast milk. To facilitate studies on the safety of lacosamide use during brea...
Autores principales: | Furugen, Ayako, Nishimura, Ayako, Umazume, Takeshi, Ishikawa, Hina, Narumi, Katsuya, Kobayashi, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472561/ https://www.ncbi.nlm.nih.gov/pubmed/37653499 http://dx.doi.org/10.1186/s40780-023-00295-w |
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