Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors

BACKGROUND: As the most lethal gynecologic cancer, ovarian cancer (OV) holds the potential of being immunotherapy-responsive. However, only modest therapeutic effects have been achieved by immunotherapies such as immune checkpoint blockade. This study aims to propose a generalized stroma-immune prog...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Duan, Mei-Han, Yuan, Qiu-Er, Li, Zhi-Ling, Luo, Chuang-Hua, Cui, Lan-Yue, Li, Li-Chao, Xiao, Ying, Zhu, Xian-Ying, Zhang, Hai-Liang, Feng, Gong-Kan, Liu, Guo-Chen, Deng, Rong, Li, Jun-Dong, Zhu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472577/
https://www.ncbi.nlm.nih.gov/pubmed/37658364
http://dx.doi.org/10.1186/s12967-023-04422-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472577/
https://www.ncbi.nlm.nih.gov/pubmed/37658364
http://dx.doi.org/10.1186/s12967-023-04422-x

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