Cargando…

Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML

BACKGROUND: Cancer patients can achieve dramatic responses to chemotherapy yet retain resistant tumor cells, which ultimately results in relapse. Although xenograft model studies have identified several cellular and molecular features that are associated with chemoresistance in acute myeloid leukemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yongping, Jiang, Shuting, He, Fuhong, Tian, Yuanyuan, Hu, Haiyang, Gao, Li, Zhang, Lin, Chen, Aili, Hu, Yixin, Fan, Liyan, Yang, Chun, Zhou, Bi, Liu, Dan, Zhou, Zihan, Su, Yanxun, Qin, Lei, Wang, Yi, He, Hailong, Lu, Jun, Xiao, Peifang, Hu, Shaoyan, Wang, Qian-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472599/
https://www.ncbi.nlm.nih.gov/pubmed/37653425
http://dx.doi.org/10.1186/s13059-023-03031-7