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Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML
BACKGROUND: Cancer patients can achieve dramatic responses to chemotherapy yet retain resistant tumor cells, which ultimately results in relapse. Although xenograft model studies have identified several cellular and molecular features that are associated with chemoresistance in acute myeloid leukemi...
Autores principales: | Zhang, Yongping, Jiang, Shuting, He, Fuhong, Tian, Yuanyuan, Hu, Haiyang, Gao, Li, Zhang, Lin, Chen, Aili, Hu, Yixin, Fan, Liyan, Yang, Chun, Zhou, Bi, Liu, Dan, Zhou, Zihan, Su, Yanxun, Qin, Lei, Wang, Yi, He, Hailong, Lu, Jun, Xiao, Peifang, Hu, Shaoyan, Wang, Qian-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472599/ https://www.ncbi.nlm.nih.gov/pubmed/37653425 http://dx.doi.org/10.1186/s13059-023-03031-7 |
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