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FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer

BACKGROUND: FAT4 (FAT Atypical Cadherin 4) is a member of the cadherin-associated protein family, which has been shown to function as a tumor suppressor by inhibiting proliferation and metastasis. The Wnt/β-catenin pathway activation is highly associated with PD-L1-associated tumor immune escape. He...

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Detalles Bibliográficos
Autores principales: Wang, Dongying, Wu, Shuying, He, Jiaxing, Sun, Luguo, Zhu, Hongming, Zhang, Yuxuan, Liu, Shanshan, Duan, Xuefeng, Wang, Yanhong, Xu, Tianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472690/
https://www.ncbi.nlm.nih.gov/pubmed/37658376
http://dx.doi.org/10.1186/s13046-023-02758-2