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The autophagic protein FYCO1 controls TNFRSF10/TRAIL receptor induced apoptosis and is inactivated by CASP8 (caspase 8)

Apoptosis is a tightly controlled cell death program executed by proteases, the so-called caspases. It plays an important role in tissue homeostasis and is often dysregulated in cancer. Here, we identified FYCO1, a protein that promotes microtubule plus end-directed transport of autophagic and endos...

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Detalles Bibliográficos
Autores principales: Coppola, Valeria, Marino, Ilaria, Warnken, Uwe, Falchi, Mario, Pasquini, Luca, Biffoni, Mauro, De Maria, Ruggero, Haas, Tobias Longin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472876/
https://www.ncbi.nlm.nih.gov/pubmed/37418591
http://dx.doi.org/10.1080/15548627.2023.2229656