Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis

In this study, new benzothiazole–pyrimidine hybrids (5a–c, 6, 7a–f, and 8–15) were designed and synthesised. Two different functionalities on the pyrimidine moiety of lead compound 4 were subjected to a variety of chemical changes with the goal of creating various functionalities and cyclisation to...

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Detalles Bibliográficos
Autores principales: Hemeda, Loah R., El Hassab, Mahmoud A., Abdelgawad, Mohamed A., Khaleel, Eman F., Abdel-Aziz, Marwa M., Binjubair, Faizah A., Al-Rashood, Sara T., Eldehna, Wagdy M., El-Ashrey, Mohamed K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472891/
https://www.ncbi.nlm.nih.gov/pubmed/37649381
http://dx.doi.org/10.1080/14756366.2023.2250575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472891/
https://www.ncbi.nlm.nih.gov/pubmed/37649381
http://dx.doi.org/10.1080/14756366.2023.2250575

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