Phase II randomised, placebo-controlled, clinical trial of interleukin-1 receptor antagonist in intracerebral haemorrhage: BLOcking the Cytokine IL-1 in ICH (BLOC-ICH)

PURPOSE: Recombinant human interleukin-1 receptor antagonist (anakinra) is an anti-inflammatory with efficacy in animal models of stroke. We tested the effect of anakinra on perihaematomal oedema in acute intracerebral haemorrhage (ICH) and explored effects on inflammatory markers. METHODS: We condu...

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Detalles Bibliográficos
Autores principales: Parry-Jones, Adrian R, Stocking, Katie, MacLeod, Mary Joan, Clarke, Brian, Werring, David J, Muir, Keith W, Vail, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472954/
https://www.ncbi.nlm.nih.gov/pubmed/37452707
http://dx.doi.org/10.1177/23969873231185208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472954/
https://www.ncbi.nlm.nih.gov/pubmed/37452707
http://dx.doi.org/10.1177/23969873231185208

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