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Betaine Mitigates Amyloid-β-Associated Neuroinflammation by Suppressing the NLRP3 and NF-κB Signaling Pathways in Microglial Cells

BACKGROUND: Microglia-driven neuroinflammation has been shown to be involved in the entire process of Alzheimer’s disease (AD). Betaine is a natural product that exhibits anti-inflammatory activity; however, the exact underlying molecular mechanisms are poorly understood. OBJECTIVE: Our study focuse...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473109/
https://www.ncbi.nlm.nih.gov/pubmed/37334594
http://dx.doi.org/10.3233/JAD-230064