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Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder involving heterogenous pathophysiological characteristics, which has become a challenge to therapeutics. The major pathophysiology of AD comprises amyloid-β (Aβ), tau, oxidative stress, and apoptosis. Recent studies indicate the signif...

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Detalles Bibliográficos
Autores principales: Basha, SK Chand, Ramaiah, Mekala Janaki, Kosagisharaf, Jagannatha Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473115/
https://www.ncbi.nlm.nih.gov/pubmed/36683512
http://dx.doi.org/10.3233/JAD-221070