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The Novel Role of Mitochondrial Citrate Synthase and Citrate in the Pathophysiology of Alzheimer’s Disease

Citrate synthase is a key mitochondrial enzyme that utilizes acetyl-CoA and oxaloacetate to form citrate in the mitochondrial membrane, which participates in energy production in the TCA cycle and linked to the electron transport chain. Citrate transports through a citrate malate pump and synthesize...

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Detalles Bibliográficos
Autores principales: Chhimpa, Neeraj, Singh, Neha, Puri, Nikkita, Kayath, Hanuman Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473122/
https://www.ncbi.nlm.nih.gov/pubmed/37393492
http://dx.doi.org/10.3233/JAD-220514