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Uncovering Diverse Mechanistic Spreading Pathways in Disease Progression of Alzheimer’s Disease

BACKGROUND: The AT[N] research framework focuses on three major biomarkers in Alzheimer’s disease (AD): amyloid-β deposition (A), pathologic tau (T), and neurodegeneration [N]. OBJECTIVE: We hypothesize that the diverse mechanisms such as A⟶T and A⟶[N] pathways from one brain region to others, may u...

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Detalles Bibliográficos
Autores principales: Yu, Zhentao, Shi, Zhuoyu, Dan, Tingting, Dere, Mustafa, Kim, Minjeong, Li, Quefeng, Wu, Guorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473126/
https://www.ncbi.nlm.nih.gov/pubmed/37662609
http://dx.doi.org/10.3233/ADR-230081