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Uncovering Diverse Mechanistic Spreading Pathways in Disease Progression of Alzheimer’s Disease
BACKGROUND: The AT[N] research framework focuses on three major biomarkers in Alzheimer’s disease (AD): amyloid-β deposition (A), pathologic tau (T), and neurodegeneration [N]. OBJECTIVE: We hypothesize that the diverse mechanisms such as A⟶T and A⟶[N] pathways from one brain region to others, may u...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473126/ https://www.ncbi.nlm.nih.gov/pubmed/37662609 http://dx.doi.org/10.3233/ADR-230081 |