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DNA Damage Response-Associated Cell Cycle Re-Entry and Neuronal Senescence in Brain Aging and Alzheimer’s Disease

Chronological aging is by far the strongest risk factor for age-related dementia and Alzheimer’s disease. Senescent cells accumulated in the aging and Alzheimer’s disease brains are now recognized as the keys to describing such an association. Cellular senescence is a classic phenomenon characterize...

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Detalles Bibliográficos
Autores principales: Wong, Genper Chi-Ngai, Chow, Kim Hei-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473156/
https://www.ncbi.nlm.nih.gov/pubmed/35848025
http://dx.doi.org/10.3233/JAD-220203