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A Potential Role for Sirtuin-1 in Alzheimer’s Disease: Reviewing the Biological and Environmental Evidence

Sirtuin-1 (Sirt1), encoded by the SIRT1 gene, is a conserved Nicotinamide adenine dinucleotide (NAD+) dependent deacetylase enzyme, considered as the master regulator of metabolism in humans. Sirt1 contributes to a wide range of biological pathways via several mechanisms influenced by lifestyle, suc...

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Detalles Bibliográficos
Autores principales: Mehramiz, Mehrane, Porter, Tenielle, O’Brien, Eleanor K., Rainey-Smith, Stephanie R., Laws, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473168/
https://www.ncbi.nlm.nih.gov/pubmed/37662612
http://dx.doi.org/10.3233/ADR-220088